Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Serotype

Neutralizing antibodies have a role in controlling hepatitis C virus (HCV) infection. A successful vaccine will need to elicit potently neutralizing antibodies that are capable of preventing the infection of genetically diverse viral isolates. However, the specificity of the neutralizing antibody re...

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Autori principali: Tarr, Alexander W., Urbanowicz, Richard A., Hamed, Mohamed R., Albecka, Anna, McClure, C. Patrick, Brown, Richard J. P., Irving, William L., Dubuisson, Jean, Ball, Jonathan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126256/
https://ncbi.nlm.nih.gov/pubmed/21325403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01332-10
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