RNA interference is mediated by 21- and 22-nucleotide RNAs

Double-stranded RNA (dsRNA) induces sequence-specific posttranscriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we demonstrate that 21- and 22-nt RNA fragments are the sequence-specific mediators of RNAi. The short interfe...

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Detalles Bibliográficos
Main Authors: Elbashir, Sayda M., Lendeckel, Winfried, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC312613/
https://ncbi.nlm.nih.gov/pubmed/11157775
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