Epitope-Specific CD8(+) T Lymphocytes Cross-Recognize Mutant Simian Immunodeficiency Virus (SIV) Sequences but Fail To Contain Very Early Evolution and Eventual Fixation of Epitope Escape Mutations during SIV Infection

Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) evade containment by CD8(+) T lymphocytes through focused epitope mutations. However, because of limitations in the numbers of viral sequences that can be sampled, traditional sequencing technologies have not provided a true...

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Detalhes bibliográficos
Main Authors: Cale, Evan M., Hraber, Peter, Giorgi, Elena E., Fischer, Will, Bhattacharya, Tanmoy, Leitner, Thomas, Yeh, Wendy W., Gleasner, Cheryl, Green, Lance D., Han, Cliff S., Korber, Bette, Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126128/
https://ncbi.nlm.nih.gov/pubmed/21307185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02420-10
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