The Leader Proteinase of Foot-and-Mouth Disease Virus Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase

The leader proteinase (L(pro)) of foot-and-mouth disease virus (FMDV) is a papain-like proteinase that plays an important role in FMDV pathogenesis. Previously, it has been shown that L(pro) is involved in the inhibition of the type I interferon (IFN) response by FMDV. However, the underlying mechan...

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Detalhes bibliográficos
Main Authors: Wang, Dang, Fang, Liurong, Li, Ping, Sun, Li, Fan, Jinxiu, Zhang, Qingye, Luo, Rui, Liu, Xiangtao, Li, Kui, Chen, Huanchun, Chen, Zhongbin, Xiao, Shaobo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126127/
https://ncbi.nlm.nih.gov/pubmed/21307201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02589-10
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