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In Vivo Fitness Associated with High Virulence in a Vertebrate Virus Is a Complex Trait Regulated by Host Entry, Replication, and Shedding

The relationship between pathogen fitness and virulence is typically examined by quantifying only one or two pathogen fitness traits. More specifically, it is regularly assumed that within-host replication, as a precursor to transmission, is the driving force behind virulence. In reality, many trait...

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Bibliografiske detaljer
Main Authors: Wargo, Andrew R., Kurath, Gael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126118/
https://ncbi.nlm.nih.gov/pubmed/21307204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01891-10
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