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In Vivo Fitness Associated with High Virulence in a Vertebrate Virus Is a Complex Trait Regulated by Host Entry, Replication, and Shedding

The relationship between pathogen fitness and virulence is typically examined by quantifying only one or two pathogen fitness traits. More specifically, it is regularly assumed that within-host replication, as a precursor to transmission, is the driving force behind virulence. In reality, many trait...

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Detalhes bibliográficos
Main Authors: Wargo, Andrew R., Kurath, Gael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126118/
https://ncbi.nlm.nih.gov/pubmed/21307204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01891-10
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