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Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

Granulomas, organized aggregates of immune cells, are a hallmark of tuberculosis, and have traditionally been thought to restrict mycobacterial growth. However, analysis of Mycobacterium marinum in zebrafish has shown that the early granuloma facilitates mycobacterial growth; uninfected macrophages...

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Main Authors: Volkman, Hannah E., Pozos, Tamara C., Zheng, John, Davis, J. Muse, Rawls, John F., Ramakrishnan, Lalita
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125975/
https://ncbi.nlm.nih.gov/pubmed/20007864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1179663
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