Altered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerases

UDP-hexose 4-epimerases play a pivotal role in lipopolysaccharide (LPS) biosynthesis and Leloir pathway. These epimerases are classified into three groups based on whether they recognize nonacetylated UDP-hexoses (Group 1), both N-acetylated and nonacetylated UDP-hexoses (Group 2) or only N-acetylat...

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Bibliographic Details
Main Authors: Bhatt, Veer S, Guo, Chu-yueh, Guan, Wanyi, Zhao, Guohui, Yi, Wen, Liu, Zhi-jie, Wang, Peng G
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125870/
https://ncbi.nlm.nih.gov/pubmed/21384454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.611
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