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Relative stability of de novo four–helix bundle proteins: Insights from coarse grained molecular simulations
We use a recently developed coarse-grained computational model to investigate the relative stability of two different sets of de novo designed four–helix bundle proteins. Our simulations suggest a possible explanation for the experimentally observed increase in stability of the four–helix bundles wi...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125866/ https://ncbi.nlm.nih.gov/pubmed/21344535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.605 |
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