SpyA, a C3-Like ADP-Ribosyltransferase, Contributes to Virulence in a Mouse Subcutaneous Model of Streptococcus pyogenes Infection ‡

Streptococcus pyogenes is an important human pathogen with an expansive repertoire of verified and putative virulence factors. Here we demonstrate that a mutant deficient in the production of the streptococcal ADP-ribosyltransferase SpyA generates lesions of reduced size in a subcutaneous mouse infe...

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Bibliographic Details
Main Authors: Hoff, Jessica S., DeWald, Mark, Moseley, Steve L., Collins, Carleen M., Voyich, Jovanka M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125853/
https://ncbi.nlm.nih.gov/pubmed/21422178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01191-10
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