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Membrane binding of an acyl-lactoferricin B antimicrobial peptide from solid-state NMR experiments and molecular dynamics simulations

One approach to the growing health problem of antibiotic resistant bacteria is the development of antimicrobial peptides (AMPs) as alternative treatments. The mechanism by which these AMPs selectively attack the bacterial membrane is not well understood, but is believed to depend on differences in m...

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Detalhes bibliográficos
Main Authors: Romo, Tod D., Bradney, Laura A., Greathouse, Denise V., Grossfield, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124939/
https://ncbi.nlm.nih.gov/pubmed/21477580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.03.017
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