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Simulating the mechanism of antimicrobial lipopeptides with all-atom molecular dynamics

The emergence of antibiotic resistant pathogens is one of the major medical concerns of the 21st century, prompting renewed interest in the development of novel antimicrobial compounds. Here we use microsecond-scale all-atom molecular dynamics simulations to characterize the structure, dynamics, and...

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Detalhes bibliográficos
Main Authors: Horn, Joshua N., Romo, Tod D., Grossfield, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030210/
https://ncbi.nlm.nih.gov/pubmed/23875688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400773q
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