Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.

As an approach to gene therapy for the respiratory manifestations of cystic fibrosis (CF), in vivo plasmid-mediated direct transfer of the normal CF transmembrane conductance regulator (CFTR) gene to the airway epithelium was investigated in mice. To evaluate the feasibility of this strategy, pRSVL,...

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Hlavní autoři: Yoshimura, K, Rosenfeld, M A, Nakamura, H, Scherer, E M, Pavirani, A, Lecocq, J P, Crystal, R G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC312463/
https://ncbi.nlm.nih.gov/pubmed/1377820
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