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Hill coefficients of dietary polyphenolic enzyme inhibitiors: can beneficial health effects of dietary polyphenols be explained by allosteric enzyme denaturing?

Inspired by a recent article by Prinz, suggesting that Hill coefficients, obtained from four parameter logistic fits to dose–response curves, represent a parameter allowing distinction between a general allosteric denaturing process and real single site enzyme inhibition, Hill coefficients of a numb...

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Main Authors: Kuhnert, Nikolai, Dairpoosh, Farnoosh, Jaiswal, Rakesh, Matei, Marius, Deshpande, Sagar, Golon, Agnieszka, Nour, Hany, Karaköse, Hande, Hourani, Nadim
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124628/
https://ncbi.nlm.nih.gov/pubmed/22287993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-011-0055-9
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