Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca(2+) uptake in human atrial fibrillation

Sarcolipin (SLN), a key regulator of cardiac sarco(endo)plasmic reticulum (SR) Ca(2+) ATPase, is predominantly expressed in atria and mediates β-adrenergic responses. Studies have shown that SLN mRNA expression is decreased in human chronic atrial fibrillation (AF) and in aortic banded mouse atria;...

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Main Authors: Shanmugam, Mayilvahanan, Molina, Cristina E., Gao, Shumin, Severac-Bastide, Renaud, Fischmeister, Rodolphe, Babu, Gopal J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124607/
https://ncbi.nlm.nih.gov/pubmed/21640081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.05.113
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