Physiological Induction of Regulatory Qa-1-Restricted CD8+ T Cells Triggered by Endogenous CD4+ T Cell Responses

T cell-dependent autoimmune diseases are characterized by the expansion of T cell clones that recognize immunodominant epitopes on the target antigen. As a consequence, for a given autoimmune disorder, pathogenic T cell clones express T cell receptors with a limited number of variable regions that d...

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Main Authors: Varthaman, Aditi, Clement, Marc, Khallou-Laschet, Jamila, Fornasa, Giulia, Gaston, Anh-Thu, Dussiot, Michael, Caligiuri, Giuseppina, Cantor, Harvey, Kaveri, Srinivas, Nicoletti, Antonino
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124544/
https://ncbi.nlm.nih.gov/pubmed/21738737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021628
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