Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homology modelling of the wild type protein and 13 variant proteins. The novel molecular models of M. gr...

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Bibliografiska uppgifter
Huvudupphovsmän: Mullins, Jonathan G. L., Parker, Josie E., Cools, Hans J., Togawa, Roberto C., Lucas, John A., Fraaije, Bart A., Kelly, Diane E., Kelly, Steven L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124474/
https://ncbi.nlm.nih.gov/pubmed/21738598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020973
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