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Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homology modelling of the wild type protein and 13 variant proteins. The novel molecular models of M. gr...

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Detalhes bibliográficos
Main Authors: Jonathan G L Mullins, Josie E Parker, Hans J Cools, Roberto C Togawa, John A Lucas, Bart A Fraaije, Diane E Kelly, Steven L Kelly
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3124474?pdf=render
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