A Small Molecule MIF Antagonist Protects against Glomerulonephritis in Lupus-prone NZB/NZW F1 and MRL/lpr Mice

Autoimmunity leads to the activation of innate effector pathways, pro-inflammatory cytokine production, and end-organ injury. Macrophage migration inhibitory factor (MIF) is an upstream activator of the innate response that mediates the recruitment and retention of monocytes via CD74 and associated...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Leng, Lin, Chen, Liang, Fan, Juan, Greven, Dorothee, Arjona, Alvaro, Du, Xin, Austin, David, Kashgarian, Michael, Yin, Zhinan, Huang, Xiao R., Lan, Hui Y., Lolis, Elias, Nikolic-Paterson, David, Bucala, Richard
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124407/
https://ncbi.nlm.nih.gov/pubmed/21106847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001767
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker