Transgenic mice generated by pronuclear injection of a yeast artificial chromosome.

Transgenic mice have become invaluable for analysing gene function and regulation in vivo. However, the size of constructs injected has been limited by the cloning capacity of conventional vectors, a constraint that could be overcome with yeast artificial chromosomes (YACs). We investigated the feas...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Schedl, A, Beermann, F, Thies, E, Montoliu, L, Kelsey, G, Schütz, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1992
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.12.3073
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