Transgenic mice generated by pronuclear injection of a yeast artificial chromosome.
Transgenic mice have become invaluable for analysing gene function and regulation in vivo. However, the size of constructs injected has been limited by the cloning capacity of conventional vectors, a constraint that could be overcome with yeast artificial chromosomes (YACs). We investigated the feas...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1992
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.12.3073 |
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