Human Leukocyte Antigen Class II Transgenic Mouse Model Unmasks the Significant Extrahepatic Pathology in Toxic Shock Syndrome

Among the exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes, the superantigens (SAgs) are the most potent T-cell activators known to date. SAgs are implicated in several serious diseases including toxic shock syndrome (TSS), Kawasaki disease, and sepsis. However, the immunopatho...

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Bibliographische Detailangaben
Hauptverfasser: Tilahun, Ashenafi Y., Marietta, Eric V., Wu, Tsung-Teh, Patel, Robin, David, Chella S., Rajagopalan, Govindarajan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124354/
https://ncbi.nlm.nih.gov/pubmed/21641398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.02.033
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