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Redistribution and Hemostatic Action of Recombinant Activated Factor VII Associated with Platelets

Clinical evidence accumulated from hemophilic patients during prophylaxis with recombinant activated factor VII (rFVIIa) suggests that the duration of the hemostatic action of rFVIIa exceeds its predicted plasma half-life. Mechanisms involved in this outcome have not been elucidated. We have investi...

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Détails bibliographiques
Auteurs principaux: Lopez-Vilchez, Irene, Hedner, Ulla, Altisent, Carmen, Diaz-Ricart, Maribel, Escolar, Gines, Galan, Ana M.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124331/
https://ncbi.nlm.nih.gov/pubmed/21641410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.02.026
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