Redistribution and Hemostatic Action of Recombinant Activated Factor VII Associated with Platelets

Clinical evidence accumulated from hemophilic patients during prophylaxis with recombinant activated factor VII (rFVIIa) suggests that the duration of the hemostatic action of rFVIIa exceeds its predicted plasma half-life. Mechanisms involved in this outcome have not been elucidated. We have investi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lopez-Vilchez, Irene, Hedner, Ulla, Altisent, Carmen, Diaz-Ricart, Maribel, Escolar, Gines, Galan, Ana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124331/
https://ncbi.nlm.nih.gov/pubmed/21641410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.02.026
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