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Altered myofilament stoichiometry in response to heart failure in a cardioprotective α-myosin heavy chain transgenic rabbit model
PURPOSE: Decreases in alpha myosin heavy chain (α-MHC) is a common feature of human heart failure (HF), while α-MHC overexpression in transgenic (TG) rabbits is cardioprotective against tachycardia-induced cardiomyopathy (TIC). Hypothesizing that MHC isoform content alterations would impact sarcomer...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124290/ https://ncbi.nlm.nih.gov/pubmed/21365772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201000116 |
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