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Effects of myosin heavy chain manipulation in experimental heart failure
The myosin heavy chain (MHC) isoforms, α- and β-MHC, are expressed in developmental- and chamber-specific patterns. Healthy human ventricle contains ∼2-10% α-MHC and these levels are reduced even further in the failing ventricle. While down-regulation of α-MHC in failing myocardium is considered com...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854276/ https://ncbi.nlm.nih.gov/pubmed/19854200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.10.013 |
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