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Control of the heparosan N-deacetylation leads to an improved bioengineered heparin

The production of the anticoagulant drug heparin from non-animal sources has a number of advantages over the current commercial production of heparin. These advantages include better source material availability, improved quality control, and reduced concerns about animal virus or prion impurities....

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Bibliographic Details
Main Authors: Wang, Zhenyu, Yang, Bo, Zhang, Zhenqing, Ly, Mellisa, Takieddin, Majde, Mousa, Shaker, Liu, Jian, Dordick, Jonathan S., Linhardt, Robert J.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124281/
https://ncbi.nlm.nih.gov/pubmed/21484210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-011-3231-5
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