Llwytho...

Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice

AXL and TYRO3, members of the TYRO3, AXL and MER (TAM) family of tyrosine kinase receptors, modulate GnRH neuronal cell migration, survival and gene expression. Axl/ Tyro3 null mice exhibit a selective loss of GnRH neurons, delayed sexual maturation and irregular estrous cycles. Here we determined w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pierce, Angela, Xu, Mei, Bliesner, Brian, Liu, Zhilin, Richards, JoAnne, Tobet, Stuart, Wierman, Margaret E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124083/
https://ncbi.nlm.nih.gov/pubmed/21539887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.04.007
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