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XAS Structural Investigation of Early Intermediates in the Mechanism of DNA Repair by Human ABH2
Human ABH2 repairs DNA lesions by using an Fe(II)- and αKG-dependent oxidative demethylation mechanism. The structure of the active site features the facial triad of protein ligands consisting of the side chains of two histidine and one aspartate residues that is common to many nonheme Fe(II) oxygen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124014/ https://ncbi.nlm.nih.gov/pubmed/21510633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101668x |
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