Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression

Cell senescence is a permanent growth arrest following extended proliferation. Cultured cancer cells including metastatic melanoma cells often appear immortal (proliferate indefinitely), while uncultured benign nevi (moles) show senescence markers. Here, with new explantation methods, we investigate...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Soo, Julia K, MacKenzie Ross, Alastair D, Kallenberg, David M, Milagre, Carla, Heung Chong, W, Chow, Jade, Hill, Lucy, Hoare, Stacey, Collinson, Rebecca S, Hossain, Mehnaz, Keith, W Nicol, Marais, Richard, Bennett, Dorothy C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2011
Aiheet:
Signaling & Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123747/
https://ncbi.nlm.nih.gov/pubmed/21418545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2011.00850.x
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