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Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients

BACKGROUND: Cyclooxygenase-2 overexpression is associated with poor outcome and resistance to platinum-based chemotherapy in ovarian cancer. We evaluated the antitumor activity and safety of the combination carboplatin plus the COX-2 inhibitor celecoxib in recurrent heavily-treated OC patients. METH...

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Main Authors: Legge, Francesco, Paglia, Amelia, D'Asta, Marco, Fuoco, Gilda, Scambia, Giovanni, Ferrandina, Gabriella
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123659/
https://ncbi.nlm.nih.gov/pubmed/21627839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-214
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