Polymorphism of Plasmodium falciparum Na(+)/H(+ )exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam

BACKGROUND: The Plasmodium falciparum NA+/H+ exchanger (pfnhe1, gene PF13_0019) has recently been proposed to influence quinine (QN) susceptibility. However, its contribution to QN resistance seems to vary geographically depending on the genetic background of the parasites. Here, the role of this ge...

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Hlavní autoři: Sinou, Véronique, Quang, Le Hong, Pelleau, Stéphane, Huong, Vu Nhu, Huong, Nguyen Thu, Tai, Le Minh, Bertaux, Lionel, Desbordes, Marc, Latour, Christine, Long, Lai Quang, Thanh, Nguyen Xuan, Parzy, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123604/
https://ncbi.nlm.nih.gov/pubmed/21669011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-164
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