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Codon usage in vertebrates is associated with a low risk of acquiring nonsense mutations
BACKGROUND: Codon usage in genomes is biased towards specific subsets of codons. Codon usage bias affects translational speed and accuracy, and it is associated with the tRNA levels and the GC content of the genome. Spontaneous mutations drive genomes to a low GC content. Active cellular processes a...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123582/ https://ncbi.nlm.nih.gov/pubmed/21651781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-87 |
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