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Codon usage in vertebrates is associated with a low risk of acquiring nonsense mutations

BACKGROUND: Codon usage in genomes is biased towards specific subsets of codons. Codon usage bias affects translational speed and accuracy, and it is associated with the tRNA levels and the GC content of the genome. Spontaneous mutations drive genomes to a low GC content. Active cellular processes a...

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Detalhes bibliográficos
Main Authors: Schmid, Pirmin, Flegel, Willy A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123582/
https://ncbi.nlm.nih.gov/pubmed/21651781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-87
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