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7-Deaza-2′-deoxyadenosine and 3-deaza-2′-deoxyadenosine replacing dA within d(A(6))-tracts: differential bending at 3′- and 5′-junctions of d(A(6))·d(T(6)) and B-DNA

7-Deaza-2′-deoxyadenosine (1, c(7)A(d)) and 3-deaza-2′-deoxyadenosine (2, c(3)A(d)) have been incorporated into d(AAAAAA) tracts replacing dA at various positions within oligonucleotides. For this purpose suitably protected phosphonates have been prepared and oligonucleotides were synthsized on soli...

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Bibliografiske detaljer
Main Authors: Seela, Frank, Grein, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312345/
https://ncbi.nlm.nih.gov/pubmed/1630898
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