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7-Deaza-2′-deoxyadenosine and 3-deaza-2′-deoxyadenosine replacing dA within d(A(6))-tracts: differential bending at 3′- and 5′-junctions of d(A(6))·d(T(6)) and B-DNA
7-Deaza-2′-deoxyadenosine (1, c(7)A(d)) and 3-deaza-2′-deoxyadenosine (2, c(3)A(d)) have been incorporated into d(AAAAAA) tracts replacing dA at various positions within oligonucleotides. For this purpose suitably protected phosphonates have been prepared and oligonucleotides were synthsized on soli...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1992
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312345/ https://ncbi.nlm.nih.gov/pubmed/1630898 |
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