Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy

BACKGROUND: Chronic inflammation plays an important role in the progression of diabetic nephropathy (DN) and that the infiltration of macrophages in glomerulus has been implicated in the development of glomerular injury. We hypothesized that the plant polyphenolic compound curcumin, which is known t...

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Bibliographic Details
Main Authors: Soetikno, Vivian, Sari, Flori R, Veeraveedu, Punniyakoti T, Thandavarayan, Rajarajan A, Harima, Meilei, Sukumaran, Vijayakumar, Lakshmanan, Arun Prasath, Suzuki, Kenji, Kawachi, Hiroshi, Watanabe, Kenichi
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123175/
https://ncbi.nlm.nih.gov/pubmed/21663638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-8-35
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