Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy

BACKGROUND: Chronic inflammation plays an important role in the progression of diabetic nephropathy (DN) and that the infiltration of macrophages in glomerulus has been implicated in the development of glomerular injury. We hypothesized that the plant polyphenolic compound curcumin, which is known t...

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Main Authors: Soetikno, Vivian, Sari, Flori R, Veeraveedu, Punniyakoti T, Thandavarayan, Rajarajan A, Harima, Meilei, Sukumaran, Vijayakumar, Lakshmanan, Arun Prasath, Suzuki, Kenji, Kawachi, Hiroshi, Watanabe, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123175/
https://ncbi.nlm.nih.gov/pubmed/21663638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-8-35
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