Effects of Memantine on Cerebrospinal Fluid Biomarkers of Neurofibrillary Pathology

Previous studies showed that memantine inhibits tau hyperphosphorylation in vitro. In this study, phosphorylated tau (P-tau) and total tau (T-tau) were measured before and after 6 month treatment with memantine in 12 subjects ranging from normal cognition with subjective memory complaints, through m...

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Hauptverfasser: Glodzik, Lidia, De Santi, Susan, Rich, Kenneth E., Brys, Miroslaw, Pirraglia, Elizabeth, Mistur, Rachel, Switalski, Remigiusz, Mosconi, Lisa, Sadowski, Martin, Zetterberg, Henrik, Blennow, Kaj, de Leon, Mony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123136/
https://ncbi.nlm.nih.gov/pubmed/19661628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1183
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