Hypometabolism and Altered Cerebrospinal Fluid Markers in Normal Apolipoprotein E E4 Carriers with Subjective Memory Complaints

BACKGROUND: We examined whether cerebral metabolic rates for glucose (CMRglc) on 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET) and cerebrospinal fluid (CSF) markers of Alzheimer’s disease (AD) are altered in cognitively normal apolipoprotein E (ApoE) E4 carriers with sub...

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Bibliografiske detaljer
Main Authors: Mosconi, Lisa, De Santi, Susan, Brys, Miroslaw, Tsui, Wai H., Pirraglia, Elizabeth, Glodzik-Sobanska, Lidia, Rich, Kenneth E., Switalski, Remigius, Mehta, Pankaj D., Pratico, Domenico, Zinkowski, Ray, Blennow, Kay, de Leon, Mony J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386268/
https://ncbi.nlm.nih.gov/pubmed/17720148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.05.030
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