Phosphorothioate substitution identifies phosphate groups important for pre-mRNA splicing.
Substitution of pre-mRNA in vitro splicing substrates with alpha-phosphorothioate ribonucleotide analogs has multiple effects on the processes of spliceosome formation and splicing. A major effect of substitution is on the splicing cleavage/ligation reactions. Substitution at the 5' splice junction...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1992
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.8.1949 |
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