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Rho-associated Kinase Connects a Cell Cycle-controlling Anchorage Signal to the Mammalian Target of Rapamycin Pathway

When deprived of anchorage to the extracellular matrix, fibroblasts arrest in G(1) phase at least in part due to inactivation of G(1) cyclin-dependent kinases. Despite great effort, how anchorage signals control the G(1)-S transition of fibroblasts remains highly elusive. We recently found that the...

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Detalhes bibliográficos
Main Authors: Park, Jung-ha, Arakawa-Takeuchi, Shiho, Jinno, Shigeki, Okayama, Hiroto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123080/
https://ncbi.nlm.nih.gov/pubmed/21561859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209114
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