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Rho-associated Kinase Connects a Cell Cycle-controlling Anchorage Signal to the Mammalian Target of Rapamycin Pathway

When deprived of anchorage to the extracellular matrix, fibroblasts arrest in G(1) phase at least in part due to inactivation of G(1) cyclin-dependent kinases. Despite great effort, how anchorage signals control the G(1)-S transition of fibroblasts remains highly elusive. We recently found that the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Jung-ha, Arakawa-Takeuchi, Shiho, Jinno, Shigeki, Okayama, Hiroto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123080/
https://ncbi.nlm.nih.gov/pubmed/21561859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209114
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