Alpha(1)-Antitrypsin Deficiency–Related Alleles Z and S and the Risk of Wegener’s Granulomatosis

OBJECTIVE: Deficiency of α(1)-antitrypsin (α(1)AT) may be a determinant of susceptibility to Wegener’s granulomatosis (WG). Several previous, mainly small, case–control studies have shown that 5–27% of patients with WG carried the α(1)AT deficiency Z allele. It is not clear whether the S allele, the...

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Detalhes bibliográficos
Main Authors: Mahr, Alfred D., Edberg, Jeffrey C., Stone, John H., Hoffman, Gary S., St. Clair, E. William, Specks, Ulrich, Dellaripa, Paul F., Seo, Philip, Spiera, Robert F., Rouhani, Farshid N., Brantly, Mark L., Merkel, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123032/
https://ncbi.nlm.nih.gov/pubmed/20827781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27742
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