Alpha(1)-Antitrypsin Deficiency–Related Alleles Z and S and the Risk of Wegener’s Granulomatosis

OBJECTIVE: Deficiency of α(1)-antitrypsin (α(1)AT) may be a determinant of susceptibility to Wegener’s granulomatosis (WG). Several previous, mainly small, case–control studies have shown that 5–27% of patients with WG carried the α(1)AT deficiency Z allele. It is not clear whether the S allele, the...

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Main Authors: Mahr, Alfred D., Edberg, Jeffrey C., Stone, John H., Hoffman, Gary S., St. Clair, E. William, Specks, Ulrich, Dellaripa, Paul F., Seo, Philip, Spiera, Robert F., Rouhani, Farshid N., Brantly, Mark L., Merkel, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123032/
https://ncbi.nlm.nih.gov/pubmed/20827781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27742
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