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Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis
Hepcidin, a hormone produced mainly by the liver, has been shown to inhibit both intestinal iron absorption and iron release from macrophages. Hemojuvelin, a glycophosphatidyl inositol–linked membrane protein, acts as a bone morphogenetic protein coreceptor to activate hepcidin expression through a...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122950/ https://ncbi.nlm.nih.gov/pubmed/21493799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-327957 |
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