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Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

Hepcidin, a hormone produced mainly by the liver, has been shown to inhibit both intestinal iron absorption and iron release from macrophages. Hemojuvelin, a glycophosphatidyl inositol–linked membrane protein, acts as a bone morphogenetic protein coreceptor to activate hepcidin expression through a...

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Detalhes bibliográficos
Main Authors: Chen, Wenjie, Huang, Franklin W., de Renshaw, Tomasa Barrientos, Andrews, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122950/
https://ncbi.nlm.nih.gov/pubmed/21493799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-327957
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