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Requirement of Npc1 and availability of cholesterol for early embryonic cell movements in zebrafish
Abstract Niemann-Pick disease, type C (NP-C), often associated with Niemann-Pick disease, type C1 (NPC1) mutations, is a cholesterol-storage disorder characterized by cellular lipid accumulation, neurodegeneration, and reduced steroid production. To study NPC1 function in vivo, we cloned zebrafish...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122913/ https://ncbi.nlm.nih.gov/pubmed/21576600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M012377 |
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