A single amino acid change restores DNA cytosine methyltransferase activity in a cloned chlorella virus pseudogene.

The chlorella virus PBCV-1 contains an open reading frame, named P17-ORF4, which differs by eight amino acids from a DNA cytosine methyltransferase, M.CviJI, encoded by a different chlorella virus IL-3A. Whereas IL-3A expresses M.CviJI, which methylates the central cytosine in (A/G)GC(T/C/G) sequenc...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Zhang, Y, Nelson, M, Van Etten, J L
Format: Artigo
Language:Inglês
Published: Oxford University Press 1992
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.7.1637
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