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A single amino acid change restores DNA cytosine methyltransferase activity in a cloned chlorella virus pseudogene.
The chlorella virus PBCV-1 contains an open reading frame, named P17-ORF4, which differs by eight amino acids from a DNA cytosine methyltransferase, M.CviJI, encoded by a different chlorella virus IL-3A. Whereas IL-3A expresses M.CviJI, which methylates the central cytosine in (A/G)GC(T/C/G) sequenc...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1992
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| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.7.1637 |
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