Randomized Pharmacokinetic and Pharmacodynamic Comparison of Fluoroquinolones for Tuberculous Meningitis

Tuberculous meningitis (TBM) is the most lethal form of tuberculosis, and new treatments that improve outcomes are required. We randomly assigned adults with TBM to treatment with standard antituberculosis treatment alone or in combination with ciprofloxacin (750 mg/12 h), levofloxacin (500 mg/12 h)...

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Hauptverfasser: Thwaites, Guy E., Bhavnani, Sujata M., Chau, Tran Thi Hong, Hammel, Jeffrey P., Török, M. Estée, Van Wart, Scott A., Mai, Pham Phuong, Reynolds, Daniel K., Caws, Maxine, Dung, Nguyen Thi, Hien, Tran Tinh, Kulawy, Robert, Farrar, Jeremy, Ambrose, Paul G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122453/
https://ncbi.nlm.nih.gov/pubmed/21502621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00064-11
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