Randomized Pharmacokinetic and Pharmacodynamic Comparison of Fluoroquinolones for Tuberculous Meningitis

Tuberculous meningitis (TBM) is the most lethal form of tuberculosis, and new treatments that improve outcomes are required. We randomly assigned adults with TBM to treatment with standard antituberculosis treatment alone or in combination with ciprofloxacin (750 mg/12 h), levofloxacin (500 mg/12 h)...

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Detalhes bibliográficos
Main Authors: Thwaites, Guy E., Bhavnani, Sujata M., Chau, Tran Thi Hong, Hammel, Jeffrey P., Török, M. Estée, Van Wart, Scott A., Mai, Pham Phuong, Reynolds, Daniel K., Caws, Maxine, Dung, Nguyen Thi, Hien, Tran Tinh, Kulawy, Robert, Farrar, Jeremy, Ambrose, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122453/
https://ncbi.nlm.nih.gov/pubmed/21502621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00064-11
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